Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.

Author(s): Biering SB, Akey DL, Wong MP, Brown WC, Lo NTN, Puerta-Guardo H, Tramontini Gomes de Sousa F, Wang C, Konwerski JR, Espinosa DA, Bockhaus NJ, Glasner DR, Li J, Blanc SF, Juan EY, Elledge SJ, Mina MJ, Beatty PR, Smith JL, Harris EJournal: SciencePMID: 33414220 January 2021
Medically important flaviviruses cause diverse disease pathologies and collectively are responsible for a major global disease burden. A contributing factor…

The effect of human mobility and control measures on the COVID-19 epidemic in China.

Author(s): Kraemer MUG, Yang CH, Gutierrez B, Wu CH, Klein B, Pigott DM, Open COVID-19 Data Working Group., du Plessis L, Faria NR, Li R, Hanage WP, Brownstein JS, Layan M, Vespignani A, Tian H, Dye C, Pybus OG, Scarpino SVJournal: SciencePMID: 32213647 March 2020
The ongoing COVID-19 outbreak expanded rapidly throughout China. Major behavioral, clinical, and state interventions have been undertaken to mitigate the…

Aggregated mobility data could help fight COVID-19.

Author(s): Buckee CO, Balsari S, Chan J, Crosas M, Grad YH, Grenfell B, Halloran ME, Kraemer MUG, Lipsitch M, Metcalf CJE, Meyers LA, Perkins TA, Santillana M, Scarpino SV, Viboud C, Wesolowski A, Schroeder AJournal: SciencePMID: 32205458 March 2020
As the coronavirus disease (COVID-19) epidemic worsens, understanding the effectiveness of public messaging and large-scale social distancing interventions is critical.…

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.

Author(s): Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, Deruff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BLJournal: SciencePMID: 33303686 February 2020
Analysis of 772 complete SARS-CoV-2 genomes from early in the Boston area epidemic revealed numerous introductions of the virus, a…