Publications

Large variation in the association between seasonal antibiotic use and resistance across multiple bacterial species and antibiotic classes

Author(s): Sun DS, Kissler SM, Kanjilal S, Olesen SW, Lipsitch M, Grad YH|Journal: medRxiv| December 2020

Understanding how antibiotic use drives resistance is crucial for guiding effective strategies to limit the spread of resistance, but the…

Reductions in commuting mobility correlate with geographic differences in SARS-CoV-2 prevalence in New York City.

Author(s): Kissler SM, Kishore N, Prabhu M, Goffman D, Beilin Y, Landau R, Gyamfi-Bannerman C, Bateman BT, Snyder J, Razavi AS, Katz D, Gal J, Bianco A, Stone J, Larremore D, Buckee CO, Grad YH|Journal: Nat Commun|PMID: 32938924| September 2020

SARS-CoV-2-related mortality and hospitalizations differ substantially between New York City neighborhoods. Mitigation efforts require knowing the extent to which these…

Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants.

Author(s): Hicks AL, Kissler SM, Mortimer TD, Ma KC, Taiaroa G, Ashcroft M, Williamson DA, Lipsitch M, Grad YH|Journal: Elife|PMID: 32602459| June 2020

Genotype-based diagnostics for antibiotic resistance represent a promising alternative to empiric therapy, reducing inappropriate antibiotic use. However, because such assays…

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period.

Author(s): Kissler SM, Tedijanto C, Goldstein E, Grad YH, Lipsitch M|Journal: Science|PMID: 32291278| May 2020

It is urgent to understand the future of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission. We used estimates of seasonality,…

Distinguishing the roles of antibiotic stewardship and reductions in outpatient visits in generating a five-year decline in antibiotic prescribing.

Author(s): Kissler SM, Klevens RM, Barnett ML, Grad YH|Journal: Clin Infect Dis|PMID: 32173727| March 2020

The mechanisms driving the recent decline in outpatient antibiotic prescribing are unknown. We estimated the extent to which reductions in…

Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics.

Author(s): Hicks AL, Kissler SM, Lipsitch M, Grad YH|Journal: PLoS Biol|PMID: 31714937| November 2019

The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is limited by the extent to which they detect genes and…