Publications

Distinguishing the roles of antibiotic stewardship and reductions in outpatient visits in generating a five-year decline in antibiotic prescribing.

Author(s): Kissler SM, Klevens RM, Barnett ML, Grad YH|Journal: Clin Infect Dis|PMID: 32173727| March 2020

The mechanisms driving the recent decline in outpatient antibiotic prescribing are unknown. We estimated the extent to which reductions in…

Two clinical prediction tools to improve tuberculosis contact investigation.

Author(s): Li R, Nordio F, Huang CC, Contreras C, Calderon R, Yataco R, Galea JT, Zhang Z, Becerra MC, Lecca L, Murray MB|Journal: Clin Infect Dis|PMID: 31905406| January 2020

Efficient contact investigation strategies are needed for the early diagnosis of TB disease and treatment of latent TB infections.

Streptococcus pyogenes with reduced susceptibility to β-lactams: how big an alarm bell?

Author(s): Hanage WP, Shelburne SA|Journal: Clin Infect Dis|PMID: 31630163| October 2019

Alexander Fleming won the Nobel Prize in 1945. In his lecture upon receipt of the prize, he warned that use…

Depletion of Susceptibles Bias in Analyses of Intra-season Waning of Influenza Vaccine Effectiveness.

Author(s): Ray GT, Lewis N, Klein NP, Daley MF, Lipsitch M, Fireman B|Journal: Clin Infect Dis|PMID: 31351439| August 2019

Bias arises in studies of waning vaccine effectiveness when higher-risk individuals are depleted from the population at-risk, at different rates…

Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data.

Author(s): Chaguza C, Heinsbroek E, Gladstone RA, Tafatatha T, Alaerts M, Peno C, Cornick JE, Musicha P, Bar-Zeev N, Kamng'ona A, Kadioglu A, McGee L, Hanage WP, Breiman RF, Heyderman RS, French N, Everett DB, Bentley SD|Journal: Clin Infect Dis|PMID: 31094423| June 2019

Pneumococcal conjugate vaccines (PCV) have reduced pneumococcal diseases globally. Pneumococcal genomic surveys elucidate PCV effects on population structure but are…

Potential for Erosion of Efficacy in Non-Inferiority Trials of Decreasing Duration of Antibiotic Therapy.

Author(s): MacFadden DR, Hanage WP|Journal: Clin Infect Dis|PMID: 30726884| February 2019

The Relative Impact of Community and Hospital Antibiotic Use on the Selection of Extended-Spectrum Beta-lactamase-Producing Escherichia coli.

Author(s): MacFadden DR, Fisman DN, Hanage WP, Lipsitch M|Journal: Clin Infect Dis|PMID: 30462185| November 2018

Antibiotic stewardship programs have traditionally focused on reducing antibiotic use in hospital. However, reducing community antibiotic prescribing could have substantial…

Challenges of vaccine effectiveness and waning studies.

Author(s): Lipsitch M|Journal: Clin Infect Dis|PMID: 30204853| September 2018

Pan-serotype Reduction in Progression of Streptococcus pneumoniae to Otitis Media After Rollout of Pneumococcal Conjugate Vaccines.

Author(s): Lewnard JA, Givon-Lavi N, Weinberger DM, Lipsitch M, Dagan R|Journal: Clin Infect Dis|PMID: 29020218| November 2017

Reductions in otitis media (OM) burden following rollout of pneumococcal conjugate vaccines (PCVs) have exceeded predictions of vaccine impact. In…

Time From Infection to Disease and Infectiousness for Ebola Virus Disease, a Systematic Review.

Author(s): Velásquez GE, Aibana O, Ling EJ, Diakite I, Mooring EQ, Murray MB|Journal: Clin Infect Dis|PMID: 26129757| October 2015

We systematically reviewed the literature to estimate the incubation and latent periods of Ebola virus disease. We found limited epidemiological…