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Publications

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Oseltamivir for treatment and prevention of pandemic influenza A/H1N1 virus infection in households, Milwaukee, 2009.

Author(s): Goldstein E, Cowling BJ, O'Hagan JJ, Danon L, Fang VJ, Hagy A, Miller JC, Reshef D, Robins J, Biedrzycki P, Lipsitch M|Journal: BMC Infect Dis|PMID: 20642862| July 2010
During an influenza pandemic, a substantial proportion of transmission is thought to occur in households. We used data on influenza…

What is the mechanism for persistent coexistence of drug-susceptible and drug-resistant strains of Streptococcus pneumoniae?

Author(s): Colijn C, Cohen T, Fraser C, Hanage W, Goldstein E, Givon-Lavi N, Dagan R, Lipsitch M|Journal: J R Soc Interface|PMID: 19940002| June 2010
The rise of antimicrobial resistance in many pathogens presents a major challenge to the treatment and control of infectious diseases.…

Distribution of vaccine/antivirals and the ‘least spread line’ in a stratified population.

Author(s): Goldstein E, Apolloni A, Lewis B, Miller JC, Macauley M, Eubank S, Lipsitch M, Wallinga J|Journal: J R Soc Interface|PMID: 19828505| May 2010
We describe a prioritization scheme for an allocation of a sizeable quantity of vaccine or antivirals in a stratified population.…

Student behavior during a school closure caused by pandemic influenza A/H1N1.

Author(s): Miller JC, Danon L, O'Hagan JJ, Goldstein E, Lajous M, Lipsitch M|Journal: PLoS One|PMID: 20463960| May 2010
Many schools were temporarily closed in response to outbreaks of the recently emerged pandemic influenza A/H1N1 virus. The effectiveness of…

Pre-dispensing of antivirals to high-risk individuals in an influenza pandemic.

Author(s): Goldstein E, Miller JC, O'Hagan JJ, Lipsitch M|Journal: Influenza Other Respir Viruses|PMID: 20167050| March 2010
We consider the net benefits of pre-dispensing antivirals to high-risk individuals during an influenza pandemic, where the measure of the…

Reconstructing influenza incidence by deconvolution of daily mortality time series.

Author(s): Goldstein E, Dushoff J, Ma J, Plotkin JB, Earn DJ, Lipsitch M|Journal: Proc Natl Acad Sci U S A|PMID: 20080801| December 2009
We propose a mathematically straightforward method to infer the incidence curve of an epidemic from a recorded daily death curve…

H1N1 vaccination and adults with underlying health conditions in the US.

Author(s): Goldstein E, Lipsitch M|Journal: PLoS Curr|PMID: 20029669| November 2009
65% of fatalities from pH1N1 infections in a large US case series occur in adults with underlying health conditions other…

Antiviral usage for H1N1 treatment: pros, cons and an argument for broader prescribing guidelines in the United States.

Author(s): Goldstein E, Lipsitch M|Journal: PLoS Curr|PMID: 20029660| October 2009
Current CDC guidelines for antiviral treatment of people with influenza like illness (ILI) effectively discourage treatment of people with no…

Use of cumulative incidence of novel influenza A/H1N1 in foreign travelers to estimate lower bounds on cumulative incidence in Mexico.

Author(s): Lipsitch M, Lajous M, O'Hagan JJ, Cohen T, Miller JC, Goldstein E, Danon L, Wallinga J, Riley S, Dowell SF, Reed C, McCarron M|Journal: PLoS One|PMID: 19742302| September 2009
An accurate estimate of the total number of cases and severity of illness of an emerging infectious disease is required…

Reproductive numbers, epidemic spread and control in a community of households.

Author(s): Goldstein E, Paur K, Fraser C, Kenah E, Wallinga J, Lipsitch M|Journal: Math Biosci|PMID: 19559715| September 2009
Many of the studies on emerging epidemics (such as SARS and pandemic flu) use mass action models to estimate reproductive…

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