Publications

On the Relative Role of Different Age Groups During Epidemics Associated With Respiratory Syncytial Virus.

Author(s): Goldstein E, Nguyen HH, Liu P, Viboud C, Steiner CA, Worby CJ, Lipsitch M|Journal: J Infect Dis|PMID: 29112722| January 2018

While circulation of respiratory syncytial virus (RSV) results in high rates of hospitalization, particularly among young children and elderly individuals,…

Simulations for designing and interpreting intervention trials in infectious diseases.

Author(s): Halloran ME, Auranen K, Baird S, Basta NE, Bellan SE, Brookmeyer R, Cooper BS, DeGruttola V, Hughes JP, Lessler J, Lofgren ET, Longini IM, Onnela JP, Özler B, Seage GR, Smith TA, Vespignani A, Vynnycky E, Lipsitch M|Journal: BMC Med|PMID: 29287587| December 2017

Interventions in infectious diseases can have both direct effects on individuals who receive the intervention as well as indirect effects…

Multinational patterns of seasonal asymmetry in human movement influence infectious disease dynamics.

Author(s): Wesolowski A, Zu Erbach-Schoenberg E, Tatem AJ, Lourenço C, Viboud C, Charu V, Eagle N, Engø-Monsen K, Qureshi T, Buckee CO, Metcalf CJE|Journal: Nat Commun|PMID: 29234011| December 2017

Seasonal variation in human mobility is globally ubiquitous and affects the spatial spread of infectious diseases, but the ability to…

Shared Genomic Variants: Identification of Transmission Routes Using Pathogen Deep-Sequence Data.

Author(s): Worby CJ, Lipsitch M, Hanage WP|Journal: Am J Epidemiol|PMID: 29149252| November 2017

Sequencing pathogen samples during a communicable disease outbreak is becoming an increasingly common procedure in epidemiologic investigations. Identifying who infected…

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru.

Author(s): Nathavitharana RR, Shi CX, Chindelevitch L, Calderon R, Zhang Z, Galea JT, Contreras C, Yataco R, Lecca L, Becerra MC, Murray MB, Cohen T|Journal: Emerg Infect Dis|PMID: 29048297| November 2017

Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among…

Displacement of sexual partnerships in trials of sexual behavior interventions: A model-based assessment of consequences.

Author(s): McCormick AW, Abuelezam NN, Fussell T, Seage GR 3rd, Lipsitch M|Journal: Epidemics|PMID: 28416219| September 2017

We investigated the impact of the displacement of sexual activity from adherent recipients of an intervention to others within or…

Vaccine testing for emerging infections: the case for individual randomisation.

Author(s): Eyal N, Lipsitch M|Journal: J Med Ethics|PMID: 28396558| September 2017

During the 2014-2015 Ebola outbreak in Guinea, Liberia and Sierra Leone, many opposed the use of individually randomised controlled trials…

Host population structure and treatment frequency maintain balancing selection on drug resistance.

Author(s): Cobey S, Baskerville EB, Colijn C, Hanage W, Fraser C, Lipsitch M|Journal: J R Soc Interface|PMID: 28835542| August 2017

It is a truism that antimicrobial drugs select for resistance, but explaining pathogen- and population-specific variation in patterns of resistance…

Improving vaccine trials in infectious disease emergencies.

Author(s): Lipsitch M, Eyal N|Journal: Science|PMID: 28706038| July 2017

Unprecedented global effort is under way to facilitate the testing of countermeasures in infectious disease emergencies. Better understanding of the…

If a Global Catastrophic Biological Risk Materializes, at What Stage Will We Recognize It?

Author(s): Lipsitch M|Journal: Health Secur|PMID: 28745911| July 2017