Publications – Page 59 – Center for Communicable Disease Dynamics

Functional characterization of bacteria isolated from ancient arctic soil exposes diverse resistance mechanisms to modern antibiotics.

Author(s): Perron GG, Whyte L, Turnbaugh PJ, Goordial J, Hanage WP, Dantas G, Desai MMJournal: PLoS OnePMID: 25807523 March 2015

Using functional metagenomics to study the resistomes of bacterial communities isolated from different layers of the Canadian high Arctic permafrost,…

Dissecting the determinants of malaria chronicity: why within-host models struggle to reproduce infection dynamics.

Author(s): Childs LM, Buckee COJournal: J R Soc InterfacePMID: 25673299 March 2015

The duration of infection is fundamental to the epidemiological behaviour of any infectious disease, but remains one of the most…

Inference of seasonal and pandemic influenza transmission dynamics.

Author(s): Yang W, Lipsitch M, Shaman JJournal: Proc Natl Acad Sci U S APMID: 25730851 March 2015

The inference of key infectious disease epidemiological parameters is critical for characterizing disease spread and devising prevention and containment measures.…

Antibiotics in agriculture and the risk to human health: how worried should we be?

Author(s): Chang Q, Wang W, Regev-Yochay G, Lipsitch M, Hanage WPJournal: Evol ApplPMID: 25861382 March 2015

The use of antibiotics in agriculture is routinely described as a major contributor to the clinical problem of resistant disease…

Modelling challenges in context: lessons from malaria, HIV, and tuberculosis.

Author(s): Childs LM, Abuelezam NN, Dye C, Gupta S, Murray MB, Williams BG, Buckee COJournal: EpidemicsPMID: 25843394 March 2015

Malaria, HIV, and tuberculosis (TB) collectively account for several million deaths each year, with all three ranking among the top…

Origin and proliferation of multiple-drug resistance in bacterial pathogens.

Author(s): Chang HH, Cohen T, Grad YH, Hanage WP, O'Brien TF, Lipsitch MJournal: Microbiol Mol Biol RevPMID: 25652543 March 2015

Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because MDR infections are often significantly harder and more…

Quantifying the impact of accessibility on preventive healthcare in sub-Saharan Africa using mobile phone data.

Author(s): Wesolowski A, O'Meara WP, Tatem AJ, Ndege S, Eagle N, Buckee COJournal: EpidemiologyPMID: 25643101 March 2015

Poor physical access to health facilities has been identified as an important contributor to reduced uptake of preventive health services…

Sequence tag-based analysis of microbial population dynamics.

Author(s): Abel S, Abel zur Wiesch P, Chang HH, Davis BM, Lipsitch M, Waldor MKJournal: Nat MethodsPMID: 25599549 March 2015

We describe sequence tag-based analysis of microbial populations (STAMP) for characterization of pathogen population dynamics during infection. STAMP analyzes the…

Stability of the pneumococcal population structure in Massachusetts as PCV13 was introduced.

Author(s): Chang Q, Stevenson AE, Croucher NJ, Lee GM, Pelton SI, Lipsitch M, Finkelstein JA, Hanage WPJournal: BMC Infect DisPMID: 25887323 February 2015

The success of 7-valent pneumococcal conjugate vaccination (PCV-7) introduced to the US childhood immunization schedule in 2000 was partially offset…

Erratum for lipsitch and inglesby, moratorium on research intended to create novel potential pandemic pathogens.

Author(s): Lipsitch M, Inglesby TVJournal: MBioPMID: 25670775 February 2015