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Publications

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A network approach to analyzing highly recombinant malaria parasite genes.

Author(s): Larremore DB, Clauset A, Buckee CO|Journal: PLoS Comput Biol|PMID: 24130474| January 2013
The var genes of the human malaria parasite Plasmodium falciparum present a challenge to population geneticists due to their extreme…

Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans.

Author(s): Lim C, Hansen E, DeSimone TM, Moreno Y, Junker K, Bei A, Brugnara C, Buckee CO, Duraisingh MT|Journal: Nat Commun|PMID: 23535659| January 2013
The macaque malaria parasite Plasmodium knowlesi has recently emerged as an important zoonosis in Southeast Asia. Infections are typically mild…

Mobile phones and malaria: modeling human and parasite travel.

Author(s): Buckee CO, Wesolowski A, Eagle NN, Hansen E, Snow RW|Journal: Travel Med Infect Dis|PMID: 23478045| January 2013
Human mobility plays an important role in the dissemination of malaria parasites between regions of variable transmission intensity. Asymptomatic individuals…

Cholera modeling: challenges to quantitative analysis and predicting the impact of interventions.

Author(s): Grad YH, Miller JC, Lipsitch M|Journal: Epidemiology|PMID: 22659546| July 2012
Several mathematical models of epidemic cholera have recently been proposed in response to outbreaks in Zimbabwe and Haiti. These models…

Nontypeable pneumococcal isolates among navajo and white mountain apache communities: are these really a cause of invasive disease?

Author(s): Scott JR, Hinds J, Gould KA, Millar EV, Reid R, Santosham M, O'Brien KL, Hanage WP|Journal: J Infect Dis|PMID: 22536000| July 2012
Pneumococci could evade pneumococcal conjugate vaccines (PCV) by modifying, mutating, or deleting vaccine-serotype capsule genes or by downregulating capsule production.…

Evolution, safety, and highly pathogenic influenza viruses.

Author(s): Lipsitch M, Plotkin JB, Simonsen L, Bloom B|Journal: Science|PMID: 22723411| June 2012
Experience with influenza has shown that predictions of virus phenotype or fitness from nucleotide sequence are imperfect and that predicting…

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates.

Author(s): Salter SJ, Hinds J, Gould KA, Lambertsen L, Hanage WP, Antonio M, Turner P, Hermans PW, Bootsma HJ, O'Brien KL, Bentley SD|Journal: Microbiology|PMID: 22403189| June 2012
The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set…

Modeling the dynamic relationship between HIV and the risk of drug-resistant tuberculosis.

Author(s): Sergeev R, Colijn C, Murray M, Cohen T|Journal: Sci Transl Med|PMID: 22623743| May 2012
The emergence of highly drug-resistant tuberculosis (TB) and interactions between TB and HIV epidemics pose serious challenges for TB control.…

Patient sharing and population genetic structure of methicillin-resistant Staphylococcus aureus.

Author(s): Ke W, Huang SS, Hudson LO, Elkins KR, Nguyen CC, Spratt BG, Murphy CR, Avery TR, Lipsitch M|Journal: Proc Natl Acad Sci U S A|PMID: 22431601| April 2012
Rates of hospital-acquired infections, specifically methicillin-resistant Staphylococcus aureus (MRSA), are increasingly being used as indicators for quality of hospital hygiene.…

Niche and neutral effects of acquired immunity permit coexistence of pneumococcal serotypes.

Author(s): Cobey S, Lipsitch M|Journal: Science|PMID: 22383809| March 2012
Over 90 capsular serotypes of Streptococcus pneumoniae, a common nasopharyngeal colonizer and major cause of pneumonia, bacteremia, and meningitis, are…

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