Author(s): Watson JA, Kissler S, Day NP, Grad YH, White NJ|Journal: medRxiv| January 2021
There is no agreed methodology for pharmacometric assessment of candidate antiviral drugs in COVID-19. The most widely used measure of…
Author(s): Sun DS, Kissler SM, Kanjilal S, Olesen SW, Lipsitch M, Grad YH|Journal: medRxiv| December 2020
Understanding how antibiotic use drives resistance is crucial for guiding effective strategies to limit the spread of resistance, but the…
Author(s): Poyraz O, Sater MRA, Miller LG, McKinnell JA, Huang SS, Grad Y|Journal: medRxiv| December 2020
Methicillin-resistant Staphylococcus aureus (MRSA) colonizes multiple body sites, and carriage is an important risk factor for MRSA infection. Successful decolonization…
Author(s): Salje H, Wesolowski A, Brown T, Kiang M, Berry IM, Lefrancq N, Fernandez S, Jarman R, Ruchusatsawat K, Iamsirithaworn S, Vandepitte WP, Suntarattiwong P, Klungthong C, Thaisomboonsuk B, Engø-Monsen K, Buckee CO, Cauchemez S, Cummings D|Journal: medRxiv| November 2020
For most pathogens, transmission is driven by interactions between the behaviours of infectious individuals, the behaviours of the wider population,…
Author(s): Inga Holmdahl, Rebecca Kahn, James Hay, Caroline O Buckee, Michael Mina|Journal: medRxiv| November 2020
Nursing homes and other long term care facilities have been disproportionately impacted by the COVID-19 pandemic. Strategies are urgently needed…
Author(s): Andy Atkeson, Michael C Droste, Michael J Mina, James Stock|Journal: medRxiv| November 2020
We assess the economic value of screening testing programs as a policy response to the ongoing COVID-19 pandemic. We find…
Author(s): Stephen M Kissler, Joseph R. Fauver, Christina Mack, Caroline Tai, Kristin Y. Shiue, Chaney Kalinich, Sarah Jednak, Isabel Ott, Chantal Vogels, Jay Wohlgemuth, James Weisberger, John DiFiori, Deverick J. Anderson, Jimmie Mancell, David Ho, Nathan D. Grubaugh, Yonatan H. Grad|Journal: medRxiv| October 2020
SARS-CoV-2 diagnostics that report viral RNA concentrations can be used to determine a patient's stage of infection, but this potential…
Author(s): Samira Asgari, Yang Luo, Kamil Slowikowski, Chuan-Chin Huang, Roger Calderon, Judith Jimenez, Rosa Yataco, Carmen Contreras, Leonid Lecca, David Jones, D. Branch Moody, Megan B. Murray, Soumya Raychaudhuri, Jerome T Galea|Journal: medRxiv| September 2020
The global burden of pulmonary tuberculosis (TB) remains a major public health problem that is particularly severe among and disproportionately…
Author(s): Tigist Menkir, Horace Cox, Canelle Poirier, Melanie Saul, Sharon Jones-Weekes, Collette Clementson, Pablo Martinez de Salazar, Mauricio Santillana, Caroline Buckee|Journal: medRxiv| September 2020
Time lags in reporting to national surveillance systems represent a major barrier for the control of infectious diseases, preventing timely…
