Publications – Page 61 – Center for Communicable Disease Dynamics

Exploring the role of competition induced by non-vaccine serotypes for herd protection following pneumococcal vaccination.

Author(s): Masala GL, Lipsitch M, Bottomley C, Flasche SJournal: J R Soc InterfacePMID: 29093131 November 2017

The competitive pressure from non-vaccine serotypes may have helped pneumococcal conjugate vaccines (PCVs) to limit vaccine-type (VT) serotype prevalence. We…

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru.

Author(s): Nathavitharana RR, Shi CX, Chindelevitch L, Calderon R, Zhang Z, Galea JT, Contreras C, Yataco R, Lecca L, Becerra MC, Murray MB, Cohen TJournal: Emerg Infect DisPMID: 29048297 November 2017

Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among…

Immunization, Antibiotic Use, and Pneumococcal Colonization Over a 15-Year Period.

Author(s): Lee GM, Kleinman K, Pelton S, Lipsitch M, Huang SS, Lakoma M, Dutta-Linn M, Rett M, Hanage WP, Finkelstein JAJournal: PediatricsPMID: 28978716 November 2017

Rates of invasive pneumococcal disease have declined since widespread introduction of pneumococcal conjugate vaccines (PCVs) in the United States. We…

Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent.

Author(s): Taylor AR, Schaffner SF, Cerqueira GC, Nkhoma SC, Anderson TJC, Sriprawat K, Pyae Phyo A, Nosten F, Neafsey DE, Buckee COJournal: PLoS GenetPMID: 29077712 October 2017

With the rapidly increasing abundance and accessibility of genomic data, there is a growing interest in using population genetic approaches…

Displacement of sexual partnerships in trials of sexual behavior interventions: A model-based assessment of consequences.

Author(s): McCormick AW, Abuelezam NN, Fussell T, Seage GR 3rd, Lipsitch MJournal: EpidemicsPMID: 28416219 September 2017

We investigated the impact of the displacement of sexual activity from adherent recipients of an intervention to others within or…

Vaccine testing for emerging infections: the case for individual randomisation.

Author(s): Eyal N, Lipsitch MJournal: J Med EthicsPMID: 28396558 September 2017

During the 2014-2015 Ebola outbreak in Guinea, Liberia and Sierra Leone, many opposed the use of individually randomised controlled trials…

Identifying climate drivers of infectious disease dynamics: recent advances and challenges ahead.

Author(s): Metcalf CJE, Walter KS, Wesolowski A, Buckee CO, Shevliakova E, Tatem AJ, Boos WR, Weinberger DM, Pitzer VEJournal: Proc Biol SciPMID: 28814655 August 2017

Climate change is likely to profoundly modulate the burden of infectious diseases. However, attributing health impacts to a changing climate…

Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi.

Author(s): Chaguza C, Cornick JE, Andam CP, Gladstone RA, Alaerts M, Musicha P, Peno C, Bar-Zeev N, Kamng'ona AW, Kiran AM, Msefula CL, McGee L, Breiman RF, Kadioglu A, French N, Heyderman RS, Hanage WP, Bentley SD, Everett DBJournal: VaccinePMID: 28711389 August 2017

Pneumococcal infections cause a high death toll in Sub Saharan Africa (SSA) but the recently rolled out pneumococcal conjugate vaccines…

Host population structure and treatment frequency maintain balancing selection on drug resistance.

Author(s): Cobey S, Baskerville EB, Colijn C, Hanage W, Fraser C, Lipsitch MJournal: J R Soc InterfacePMID: 28835542 August 2017

It is a truism that antimicrobial drugs select for resistance, but explaining pathogen- and population-specific variation in patterns of resistance…

Improving vaccine trials in infectious disease emergencies.

Author(s): Lipsitch M, Eyal NJournal: SciencePMID: 28706038 July 2017

Unprecedented global effort is under way to facilitate the testing of countermeasures in infectious disease emergencies. Better understanding of the…