Publications

Using predicted imports of 2019-nCoV cases to determine locations that may not be identifying all imported cases.

Author(s): De Salazar PM, Niehus R, Taylor A, Buckee C, Lipsitch MJournal: medRxivPMID: 32511458 February 2020

Cases from the ongoing outbreak of atypical pneumonia caused by the 2019 novel coronavirus (2019-nCoV) exported from mainland China can…

Rapid inference of antibiotic resistance and susceptibility by genomic neighbour typing.

Author(s): Břinda K, Callendrello A, Ma KC, MacFadden DR, Charalampous T, Lee RS, Cowley L, Wadsworth CB, Grad YH, Kucherov G, O'Grady J, Baym M, Hanage WPJournal: Nat MicrobiolPMID: 32042129 February 2020

Surveillance of drug-resistant bacteria is essential for healthcare providers to deliver effective empirical antibiotic therapy. However, traditional molecular epidemiology does…

Potential impact of outpatient stewardship interventions on antibiotic exposures of common bacterial pathogens.

Author(s): Tedijanto C, Grad YH, Lipsitch MJournal: ElifePMID: 32022685 February 2020

The relationship between antibiotic stewardship and population levels of antibiotic resistance remains unclear. In order to better understand shifts in…

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.

Author(s): Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, Deruff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BLJournal: SciencePMID: 33303686 February 2020

Analysis of 772 complete SARS-CoV-2 genomes from early in the Boston area epidemic revealed numerous introductions of the virus, a…

Previously undetected super-spreading of Mycobacterium tuberculosis revealed by deep sequencing.

Author(s): Lee RS, Proulx JF, McIntosh F, Behr MA, Hanage WPJournal: ElifePMID: 32014110 February 2020

Tuberculosis disproportionately affects the Canadian Inuit. To address this, it is imperative we understand transmission dynamics in this population. We…

RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates.

Author(s): Palace SG, Wang Y, Rubin DH, Welsh MA, Mortimer TD, Cole K, Eyre DW, Walker S, Grad YHJournal: ElifePMID: 32011233 February 2020

Increasing resistance to ceftriaxone, the last antibiotic recommended for empiric gonorrhea treatment, poses an urgent public health threat. However, the…

Patients’ perspectives of tuberculosis treatment challenges and barriers to treatment adherence in Ukraine: a qualitative study.

Author(s): Aibana O, Dauria E, Kiriazova T, Makarenko O, Bachmaha M, Rybak N, Flanigan TP, Petrenko V, Becker AE, Murray MBJournal: BMJ OpenPMID: 32014870 February 2020

To understand the challenges faced by patients with tuberculosis (TB) and factors that influence TB treatment adherence in Ukraine.