Author(s): Azarian T, Grant LR, Arnold BJ, Hammitt LL, Reid R, Santosham M, Weatherholtz R, Goklish N, Thompson CM, Bentley SD, O'Brien KL, Hanage WP, Lipsitch M|Journal: PLoS Pathog|PMID:29617440| April 2018
In the United States, the introduction of the heptavalent pneumococcal conjugate vaccine (PCV) largely eliminated vaccine serotypes (VT); non-vaccine serotypes…
Author(s): Kahn R, Hitchings M, Bellan S, Lipsitch M|Journal: Clin Trials|PMID:29374974| April 2018
Background/aims Network structure and individuals' level of exposure to a pathogen can impact results from efficacy evaluation studies of interventions…
Author(s): MacFadden DR, McGeer A, Athey T, Perusini S, Olsha R, Li A, Eshaghi A, Gubbay JB, Hanage WP|Journal: Emerg Infect Dis|PMID:29460729| March 2018
Adequacy of the current clinical definition of institutional influenza outbreaks is unclear. We performed a retrospective genome sequencing and epidemiologic…
Author(s): Arnold BJ, Gutmann MU, Grad YH, Sheppard SK, Corander J, Lipsitch M, Hanage WP|Journal: Genetics|PMID:29330348| March 2018
The impact of epistasis on the evolution of multi-locus traits depends on recombination. While sexually reproducing eukaryotes recombine so frequently…
Author(s): Peak CM, Reilly AL, Azman AS, Buckee CO|Journal: PLoS Negl Trop Dis|PMID:29489815| February 2018
Oral cholera vaccination is an approach to preventing outbreaks in at-risk settings and controlling cholera in endemic settings. However, vaccine-derived…