CCDD faculty are providing cutting-edge data, tools, and policy recommendations in the fight against COVID-19. Explore what they have shared and discovered below. Entries are listed in reverse chronological order and updated daily.
January 2021
- Estimating internationally imported cases during the early COVID-19 pandemicJanuary 12
- Tigist F. Menkir, Taylor Chin, James A. Hay, Erik D. Surface, Pablo M. De Salazar, Caroline O. Buckee, Alexander Watts, Kamran Khan, Ryan Sherbo, Ada W.C. Yan, Michael J. Mina, Marc Lipsitch, Rene Niehus
- Testing SARS-CoV-2 vaccine efficacy through deliberate natural viral exposureJanuary 5
- Nir Eyal, Marc Lipsitch
- Nowcasting for Real-Time COVID-19 Tracking in New York City: Evaluation Study Using Reportable Disease Data From the Early Stages of the PandemicJanuary 4
- Sharon K. Greene, Sarah F. McGough, Gretchen M. Culp, Laura E. Graf, Marc Lipsitch, Nicolas A. Menzies, Rebecca Kahn
- Phase-3 Randomized Controlled Trials on Exclusion of Participants With Kidney Disease in COVID-19January 1
- Api Chewcharat, Yuan-Ting Chang, Meghan E. Sise, Roby P. Bhattacharyya, Megan B. Murray, Sagar U. Nigwekar
December 2020
- COVID-19 testing: One size does not fit allDecember 21
- Michael J. Mina, Kristian G. Andersen
- The Ethics of Continuing Placebo in SARS-CoV-2 Vaccine TrialsDecember 14
- Annette Rid, Marc Lipsitch, Franklin G. Miller
- Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading eventsDecember 10
- Jacob E. Lemieux, Katherine J. Siddle, Bennett M. Shaw, Christine Loreth, Stephen F. Schaffner, Adrianne Gladden-Young, Gordon Adams, Timelia Fink, Christopher H. Tomkins-Tinch, Lydia A. Krasilnikova, Katherine C. DeRuff, Melissa Rudy, Matthew R. Bauer, Kim A. Lagerborg, Erica Normandin, Sinéad B. Chapman, Steven K. Reilly, Melis N. Anahtar, Aaron E. Lin, Amber Carter, Cameron Myhrvold, Molly E. Kemball, Sushma Chaluvadi, Caroline Cusick, Katelyn Flowers, Anna Neumann, Felecia Cerrato, Maha Farhat, Damien Slater, Jason B. Harris, John A. Branda, David Hooper, Jessie M. Gaeta, Travis P. Baggett, James O’Connell, Andreas Gnirke, Tami D. Lieberman, Anthony Philippakis, Meagan Burns, Catherine M. Brown, Jeremy Luban, Edward T. Ryan, Sarah E. Turbett, Regina C. LaRocque, William P. Hanage, Glen R. Gallagher, Lawrence C. Madoff, Sandra Smole, Virginia M. Pierce, Eric Rosenberg, Pardis C. Sabeti, Daniel J. Park, Bronwyn L. MacInnis
- Assessing the age specificity of infection fatality rates for COVID-19: systematic review, meta-analysis, and public policy implicationsDecember 8
- Andrew T. Levin, William P. Hanage, Nana Owusu-Boaitey, Kensington B. Cochran, Seamus P. Walsh, Gideon Meyerowitz-Katz
- Persistence and Evolution of SARS-CoV-2 in an Immunocompromised HostDecember 3
- Bina Choi, Manish C. Choudhary, James Regan, Jeffrey A. Sparks, Robert F. Padera, Xueting Qiu, Isaac H. Solomon, Hsiao-Hsuan Kuo, Julie Boucau, Kathryn Bowman, U. Das Adhikari, Marisa L. Winkler, Alisa A. Mueller, Tiffany Y-T. Hsu, Michaël Desjardins, Lindsey R. Baden, Brian T. Chan, Bruce D. Walker, Mathias Lichterfeld, Manfred Brigl, Douglas S. Kwon, Sanjat Kanjilal, Eugene T. Richardson, A. Helena Jonsson, Galit Alter, Amy K. Barczak, William P. Hanage, Xu G. Yu, Gaurav D. Gaiha, Michael S. Seaman, Manuela Cernadas, Jonathan Z. Li
November 2020
- Test sensitivity is secondary to frequency and turnaround time for COVID-19 screeningNovember 20
- Daniel B. Larremore, Bryan Wilder, Evan Lester, Soraya Shehata, James M. Burke, James A. Hay, Milind Tambe, Michael J. Mina, Roy Parker
- Characteristics of Clinically Asymptomatic Patients with SARS-CoV-2 Infections, Case SeriesNovember 17
- Miki Goldenfeld, Ran Nir-Paz, Gadi Segal, Elhanan Bar-On, Ella Mendelson, Michal Mandelboim, Dana G. Wolf, Edith M. Marom, Tomer Israely, Hagit Achdout, Galia Rahav, William Hanage, Gili Regev-Yochay
- Big data and simple models used to track the spread of COVID-19 in citiesNovember 10
- Kevin C. Ma, Marc Lipsitch
- COVID-19: US federal accountability for entry, spread, and inequities—lessons for the futureNovember 2
- William P. Hanage, Christian Testa, Jarvis T. Chen, Letitia Davis, Elise Pechter, Peg Seminario, Mauricio Santillana, Nancy Krieger
- Measuring mobility to monitor travel and physical distancing interventions: a common framework for mobile phone data analysisNovember 1
- Nishant Kishore, Mathew V. Kiang, Kenth Engø-Monsen, Navin Vembar, Andrew Schroeder, Satchit Balsari, Caroline O. Buckee
October 2020
- On the effect of age on the transmission of SARS-CoV-2 in households, schools and the communityOctober 29
- Edward Goldstein, Marc Lipsitch, Muge Cevik
- US racial and ethnic data for COVID-19 cases: still missing in actionOctober 22
- Nancy Krieger, Christian Testa, William P. Hanage, Jarvis T. Chen
- Understanding COVID-19 vaccine efficacyOctober 21
- Marc Lipsitch, Natalie E. Dean
- Lockdown measures and relative changes in the age-specific incidence of SARS-CoV-2 in SpainOctober 20
- P.M. De Salazar, D. Gómez-Barroso, D. Pampaka, J.M. Gil, B. Peñalver, C. Fernández-Escobar, M. Lipsitch, A. Larrauri, E. Goldstein, M.A. Hernán
- Scientific consensus on the COVID-19 pandemic: we need to act nowOctober 15
- Nisreen A. Alwan, Rochelle Ann Burgess, Simon Ashworth, Rupert Beale, Nahid Bhadelia, Debby Bogaert, Jennifer Dowd, Isabella Eckerle, Lynn R. Goldman, Trisha Greenhalgh, Deepti Gurdasani, Adam Hamdy, William P. Hanage, Emma B. Hodcroft, Zoë Hyde, Paul Kellam, Michelle Kelly-Irving, Florian Krammer, Marc Lipsitch, Alan McNally, Martin McKee, Ali Nouri, Dominic Pimenta, Viola Priesemann, Harry Rutter, Joshua Silver, Devi Sridhar, Charles Swanton, Rochelle, P. Walensky, Gavin Yamey, Hisham Ziauddeen
- The role of environmental factors on transmission rates of the COVID-19 outbreak: an initial assessment in two spatial scalesOctober 12
- Canelle Poirier, Wei Luo, Maimuna S. Majumder, Dianbo Liu, Kenneth D. Mandl, Todd A. Mooring, Mauricio Santillana
- Cross-reactive memory T cells and herd immunity to SARS-CoV-2October 6
- Marc Lipsitch, Yonatan H. Grad, Alessandro Sette, Shane Crotty
September 2020
- The use of mobile phone data to inform analysis of COVID-19 pandemic epidemiologySeptember 30
- Kyra H. Grantz, Hannah R. Meredith, Derek A. T. Cummings, C. Jessica E. Metcalf, Bryan T. Grenfell, John R. Giles, Shruti Mehta, Sunil Solomon, Alain Labrique, Nishant Kishore, Caroline O. Buckee, Amy Wesolowski
- Rethinking Covid-19 Test Sensitivity — A Strategy for ContainmentSeptember 30
- Michael J. Mina, Roy Parker, Daniel B. Larremore
- SARS-CoV-2 Transmission Dynamics Should Inform PolicySeptember 23
- Muge Cevik, Julia Marcus, Caroline Buckee, Tara Smith
- Immune life history, vaccination, and the dynamics of SARS-CoV-2 over the next 5 yearsSeptember 21
- Chadi M. Saad-Roy, Caroline E. Wagner, Rachel E. Baker, Sinead E. Morris, Jeremy Farrar, Andrea L. Graham, Simon A. Levin, Michael J. Mina, C Jessica E. Metcalf, Bryan T. Grenfell
- Reductions in commuting mobility correlate with geographic differences in SARS-CoV-2 prevalence in New York CitySeptember 16
- Stephen M. Kissler, Nishant Kishore, Malavika Prabhu, Dena Goffman, Yaakov Beilin, Ruth Landau, Cynthia Gyamfi-Bannerman, Brian T. Bateman, Jon Snyder, Armin S. Razavi, Daniel Katz, Jonathan Gal, Angela Bianco, Joanne Stone, Daniel Larremore, Caroline O. Buckee, Yonatan H. Grad
- Every Body Counts: Measuring Mortality From the COVID-19 PandemicSeptember 11
- Mathew V. Kiang, Rafael A. Irizarry, Caroline O. Buckee, Satchit Balsari
- Individual quarantine versus active monitoring of contacts for the mitigation of COVID-19: a modelling studySeptember 1
- Corey M. Peak, Rebecca Kahn, Yonatan H. Grad, Lauren M. Childs, Ruoran Li, Marc Lipsitch, Caroline O. Buckee
- US-county level variation in intersecting individual, household and community characteristics relevant to COVID-19 and planning an equitable response: a cross-sectional analysisSeptember 1
- Companion application
- Taylor Chin, Rebecca Kahn, Ruoran Li, Jarvis T. Chen, Nancy Krieger, Caroline O. Buckee, Satchit Balsari, Mathew V. Kiang
- Potential Biases Arising from Epidemic Dynamics in Observational Seroprotection StudiesSeptember 1
- Rebecca Kahn, Lee Kennedy-Shaffer, Yonatan H. Grad, James M. Robins, Marc Lipsitch
August 2020
- Real-Time Forecasting of the COVID-19 Outbreak in Chinese Provinces: Machine Learning Approach Using Novel Digital Data and Estimates From Mechanistic ModelsAugust 17
- Canelle Poirier, Dianbo Liu, Leonardo Clemente, Xiyu Ding, Matteo Chinazzi, Jessica Davis, Alessandro Vespignani, Mauricio Santillana
- Individual model forecasts can be misleading, but together they are usefulAugust 11
- Caroline O. Buckee, Michael A. Johansson
- Seroprevalence of SARS-CoV-2 in Hong Kong returneesAugust 1
- William P. Hanage, Victor I. Vincent, Nicola M. Low
July 2020
- Reopening Primary Schools during the PandemicJuly 29
- Meira Levinson, Muge Cevik, Marc Lipsitch
- Opinion: It’s ethical to test promising coronavirus vaccines against less-promising onesJuly 22
- Nir Eyal, Marc Lipsitch
- SARS-CoV-2 Titers in Wastewater Are Higher than Expected from Clinically Confirmed CasesJuly 21
- Fuqing Wu, Jianbo Zhang, Amy Xiao, Xiaoqiong Gu, Wei Lin Lee, Federica Armas, Kathryn Kauffman, William Hanage, Mariana Matus, Newsha Ghaeli, Noriko Endo, Claire Duvallet, Mathilde Poyet, Katya Moniz, Alex D. Washburne, Timothy B. Erickson, Peter R. Chai, Janelle Thompson, Eric J. Alm
- Implications of test characteristics and population seroprevalence on ‘immune passport’ strategiesJuly 20
- Daniel B. Larremore, Kate M. Bubar, Yonatan H. Grad
- Making sense of mutation: what D614G means for the COVID-19 pandemic remains unclearJuly 2
- Nathan D. Grubaugh, William P. Hanage, Angela L. Rasmussen
- Identifying Locations with Possible Undetected Imported Severe Acute Respiratory Syndrome Coronavirus 2 Cases by Using Importation PredictionsJuly 1
- Pablo Martinez De Salazar, René Niehus, Aimee Taylor, Caroline O’Flaherty Buckee, Marc Lipsitch
June 2020
- Seroepidemiologic Study Designs for Determining SARS-COV-2 Transmission and ImmunityJune 16
- Hannah Clapham, James Hay, Isobel Routledge, Saki Takahashi, Marc Choisy, Derek Cummings, Bryan Grenfell, C. Jessica E Metcalf, Michael Mina, Isabel Rodriguez Barraquer, Henrik Salje, Clarence C. Tam
- Patients With Cancer Appear More Vulnerable to SARS-CoV-2: A Multicenter Study During the COVID-19 OutbreakJune 10
- Mengyuan Dai, Dianbo Liu, Miao Liu, Fuxiang Zhou, Guiling Li, Zhen Chen, Zhian Zhang, Hua You, Meng Wu, Qichao Zheng, Yong Xiong, Huihua Xiong, Chun Wang, Changchun Chen, Fei Xiong, Yan Zhang, Yaqin Peng, Siping Ge, Bo Zhen, Tingting Yu, Ling Wang, Hua Wang, Yu Liu, Yeshan Chen, Junhua Mei, Xiaojia Gao, Zhuyan Li, Lijuan Gan, Can He, Zhen Li, Yuying Shi, Yuwen Qi, Jing Yang, Daniel G. Tenen, Li Chai, Lorelei A. Mucci, Mauricio Santillana and Hongbing Cai
- A Global Immunological Observatory to meet a time of pandemicsJune 8
- Michael J. Mina, C. Jessica E Metcalf, Adrian B. McDermott, Daniel C. Douek, Jeremy Farrar, Bryan T. Grenfell
- Building an International Consortium for Tracking Coronavirus Health StatusJune 2
- Eran Segal, Feng Zhang, Xihong Lin, Gary King, Ophir Shalem, Smadar Shilo, William E. Allen, Faisal Alquaddoomi, Han Altae-Tran, Simon Anders, Ran Balicer, Tal Bauman, Ximena Bonilla, Gisel Booman, Andrew T. Chan, Ori Cohen, Silvano Coletti, Natalie Davidson, Yuval Dor, David A. Drew, Olivier Elemento, Georgina Evans, Phil Ewels, Joshua Gale, Amir Gavrieli, Benjamin Geiger, Yonatan H. Grad, et al.
May 2020
- COVID-19 Preparedness in Malawi: A National Facility-Based Critical Care AssessmentMay 25
- Paul D. Sonenthal, Jones Masiye, Noel Kasomekera, Regan H. Marsh, Emily B. Wroe, Kirstin W. Scott, Ruoran Li, Megan B. Murray, Alice Bukhman, Emilia Connolly, Tadala Minyaliwa, Martha Katete, Grace Banda, Mulinda Nyirenda, Shada A. Rouhani
- Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic periodMay 22
- Stephen M. Kissler, Christine Tedijanto, Edward Goldstein, Yonatan H. Grad, Marc Lipsitch
- To Interpret the SARS-CoV-2 Test, Consider the Cycle Threshold ValueMay 21
- Michael Tom, Michael Mina
- Phylogenetic interpretation during outbreaks requires cautionMay 19
- Ch. Julián Villabona-Arenas, William P. Hanage, Damien C. Tully
- Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forwardMay 19
- J.E. Bryant, A.S. Azman, M.J. Ferrari, B.F. Arnold, M.F. Boni, Y. Boum, K. Hayford, F.J. Luquero, M.J. Mina, I. Rodriguez-Barraquer, J.T. Wu, D. Wade, G. Vernet, D.T. Leung
- Wrong but Useful — What COVID-19 Epidemiologic Models Can and Cannot Tell UsMay 15
- Inga Holmdahl, Caroline Buckee
- Leveraging Africa’s preparedness towards the next phase of the COVID-19 pandemic May 14
- Madikay Senghore, Merveille K. Savi, Bénédicte Gnangnon, William P. Hanage, Iruka N. Okeke
- Human Challenge Studies to Accelerate Coronavirus Vaccine LicensureMay 11
- Nir Eyal, Marc Lipsitch, Peter G. Smith
- Testing COVID-19 therapies to prevent progression of mild diseaseMay 6
- Marc Lipsitch, Stanley Perlman, Matthew K. Waldor
- Estimated Demand for US Hospital Inpatient and Intensive Care Unit Beds for Patients With COVID-19 Based on Comparisons With Wuhan and Guangzhou, ChinaMay 6
- Ruoran Li, Caitlin Rivers, Qi Tan, Megan B. Murray, Eric Toner, Marc Lipsitch
- Effect of non-pharmaceutical interventions to contain COVID-19 in ChinaMay 4
- Shengjie Lai, Nick W. Ruktanonchai, Liangcai Zhou, Olivia Prosper, Wei Luo, Jessica R. Floyd, Amy Wesolowski, Mauricio Santillana, Chi Zhang, Xiangjun Du, Hongjie Yu, Andrew J. Tatem
- The effect of human mobility and control measures on the COVID-19 epidemic in ChinaMay 1
- Moritz U. G. Kraemer, Chia-Hung Yang, Bernardo Gutierrez, Chieh-Hsi Wu, Brennan Klein, David M. Pigott, Open COVID-19 Data Working Group, Louis du Plessis, Nuno R. Faria, Ruoran Li, William P. Hanage, John S. Brownstein, Maylis Layan, Alessandro Vespignani, Huaiyu Tian, Christopher Dye, Oliver G. Pybus, Samuel V. Scarpino
- Reopening ScenariosMay 1
- David Baqaee, Emmanuel Farhi, Michael J. Mina, James H. Stock
April 2020
- Temporal rise in the proportion of younger adults and older adolescents among coronavirus disease (COVID-19) cases following the introduction of physical distancing measures, Germany, March to April 2020April 30
- Edward Goldstein, Marc Lipsitch
- Coronavirus: sampling now for future analysisApril 28
- David Thaler, Marc Lipsitch
- Antibody testing will enhance the power and accuracy of COVID-19-prevention trialsApril 27
- Marc Lipsitch, Rebecca Kahn, Michael Mina
- COVID-19 Positive Cases, Evidence on the Time Evolution of the Epidemic or An Indicator of Local Testing Capabilities? A Case Study in the United StatesApril 14
- Justin Kaashoek, Mauricio Santillana
- Aggregated mobility data could help fight COVID-19April 10
- Caroline O. Buckee, Satchit Balsari, Jennifer Chan, Mercè Crosas, Francesca Dominici, Urs Gasser, Yonatan H. Grad, Bryan Grenfell, M. Elizabeth Halloran, Moritz U. G. Kraemer, Marc Lipsitch, C. Jessica E. Metcalf, Lauren Ancel Meyers, T. Alex Perkins, Mauricio Santillana, et al.
- Nowcasting by Bayesian Smoothing: A flexible, generalizable model for real-time epidemic trackingApril 6
- Bayesian Nowcasting R Package (“NobBS”)
- Sarah F. McGough, Michael A. Johansson, Marc Lipsitch, Nicolas A. Menzies
- Using observational data to quantify bias of traveller-derived COVID-19 prevalence estimates in Wuhan, ChinaApril 1
- Rene Niehus, Pablo M. De Salazar, Aimee R. Taylor, Marc Lipsitch
- Considering Public Purpose in the Time of COVID-19April
- Colin O’Leary, Amritha Jayanti, Michael Mina
March 2020
- Estimating case fatality rates of COVID-19March 31
- Marc Lipsitch
- Defining the Epidemiology of COVID-19 — Studies NeededMarch 26
- Marc Lipsitch, David L. Swerdlow, Lyn Finelli
- Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, ChinaMarch 19
- Addendum
- Joseph T. Wu, Kathy Leung, Mary Bushman, Nishant Kishore, Rene Niehus, Pablo M. de Salazar, Benjamin J. Cowling, Marc Lipsitch, Gabriel M. Leung
- The Role of Environmental Factors on Transmission Rates of the COVID-19 Outbreak: An Initial Assessment in Two Spatial ScalesMarch 12
- Canelle Poirier, Wei Luo, Maimuna S. Majumder, Dianbo Liu, Kenneth Mandl, Todd Mooring, Mauricio Santillana
February 2020
- Scenario exploration for SARS-CoV-2 infectionsFebruary 25
- Developed by the Center for Communicable Disease Dynamics at the Harvard T.H. Chan School of Public Health: Rebecca Kahn, Stephen Kissler, Nishant Kishore, Marc Lipsitch, in collaboration with Health Department colleagues
Blogs
- COVID-19 Vaccines and Herd Immunity
- Marc Lipsitch
- Declaration of Dr. Marc Lipsitch and Emma Accorsi regarding Oregon Temporary rule 437-001-0749
- Marc Lipsitch, Emma Accorsi
- Protecting the Public’s Health During Protests Against Systemic Racism
- CCDD students, post-docs, faculty, and alumni
- Mutation, Adaptation, and Virus Genomes – A Primer for the Public
- W.P. Hanage, Xueting Qiu
- Translation in Mandarin available here.
- nCOV – Making Sense of an Epidemic
- Seasonality of SARS-CoV-2: Will COVID-19 go away on its own in warmer weather?
- Marc Lipsitch
- Journalists and Scientists – Working Together on COVID-19
- William Hanage, Marc Lipsitch